TRIMERIC AUTOTRANSPORTER ADHESINS IN MEMBERS OF THE BURKHOLDERIA CEPACIA COMPLEX: A MULTIFUNCTIONAL FAMILY OF PROTEINS IMPLICATED IN VIRULENCE

Trimeric autotransporter adhesins in members of the Burkholderia cepacia complex: a multifunctional family of proteins implicated in virulence

Trimeric autotransporter adhesins (TAAs) are multimeric surface proteins, involved in various biological traits of pathogenic Gram-negative bacteria including adherence, biofilm formation, invasion, survival within eukaryotic cells, serum resistance and cytotoxicity.TAAs have a modular architecture composed by a conserved membrane-anchored C-termin

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Dermatological Problems of Brachycephalic Dogs

Brachycephalic dogs are not only affected by brachycephalic obstructive airway syndrome (BOAS), but are also frequently referred to veterinary dermatologists for skin conditions, zilla water conditioner with English bulldogs and pugs particularly over-represented.Some skin diseases, such as skin fold dermatitis, are directly associated with the abn

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Observational cohort study to validate SEARCH, a novel hierarchical algorithm to define long-term outcomes after pulmonary embolism

Background Chronic hamamelis crema dyspnoea and exercise impairment are common after acute pulmonary embolism (PE) but are not defined and quantified sufficiently to serve as outcomes in clinical trials.The planned project will clinically validate a novel method to determine discrete, clinically meaningful diagnoses after acute PE.The method uses a

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